Advances in Blood-based Biomarkers and Disease-Modifying Anti-Amyloid Antibody Therapies for Early-Stage Alzheimer’s Disease

Program Description

This webcast provides an update on the blood-based markers (BBMs) improve randomized clinical trials (RCTs) design and conduct of Alzheimer’s disease. It remains to be determined if the data available on BBMs are strong enough to replace CSF and PET biomarkers as entry criteria and monitoring tools in RCTs. Strategies to optimize and guide disease-modifying anti-amyloid antibody (AAA) therapies based on BBMs in managing patients with early-stage AD.

Intended Audience

Neurologists, nurse practitioners, and physician assistants involved in Alzheimer’s disease patient care

Commercial Supporter

This activity is supported by an educational grant from Eisai, Inc.

Educational Objectives

Upon completion of the educational activity, participants should be able to:

• Summarize the pathophysiology and the clinical presentation of Alzheimer’s disease (AD)
• Assess the blood-based biomarkers in diagnosing early-stage AD and its utility in the prevention
• Identify strategies to optimize disease-modifying anti-amyloid antibody (AAA) therapies in managing patients with early-stage AD

Accredited Providers

The University of Cincinnati, Amedco, and MedNet have collaborated to design and execute this activity.

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by Amedco LLC and MedNet. Amedco LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

Amedco Joint Accreditation #4008163.

Physicians (ACCME) Credit Designation

Designation Statement

Amedco LLC designates this enduring activity for a maximum of 1.50 AMA PRA Category 1 Credits^TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Nurses (ANCC) Credit Designation

Designation Statement

Amedco LLC designates this enduring material activity for a maximum of 1.50 ANCC contact hours.

Additional Credit Information

Physician Assistants/Associates
AAPA accepts AMA PRA Category 1 Credit(s)^TM for the PRA from organizations accredited by ACCME. Maximum of 1.50 hours.

Through an agreement between the American Medical Association (AMA) and the European Union of Medical Specialists, physicians and healthcare providers may convert CME/CE PRA Category 1 Credits^TM to an equivalent number of European CME Credits^® (ECMECs^®). The UEMS-EACCME^® has mutual recognition agreements with the AMA for live events and e-learning materials.

Nurse Practitioners
The American Association of Nurse Practitioners (AANP) recognizes the Accreditation Council for Continuing Medical Education (ACCME) and the American Nurses Credentialing Center (ANCC) as approved accreditors and allow reciprocity for AANPCP continuing education credit. Maximum of 1.50 hours.

Conflict of Interests Policy

It is the policy of the Amedco to ensure activity content is balanced, independent, objective and based on scientific best-evidence. All persons in a position to control content (i.e., course director, planning committee member and speaker) were required to disclose any relevant financial relationship with a commercial entity relative to the content of his/her presentation.

Every person in a position to control content reported he/she does not have any relevant financial relationships with industry (relative to the content of his/her presentation) to disclose.

Disclosure of Unlabeled Use

It is the policy of the Amedeo to inform each speaker of his/her responsibility to disclose to the attendees when products or procedures discussed are off-label, unlabeled, experimental, and/or investigational (not FDA approved) and of any limitations on the information that is presented, such as data that are preliminary or that represent ongoing research, interim analyses, and/or unsupported opinion.

Each speaker reported he/she will notify the audience if/when discussion includes off-label, unlabeled, experimental, and/or investigational (not FDA approved) information or limited use references within the content of his/her presentation.

Disclaimer

The information provided at this educational initiative is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition.

Non-Endorsement of Products

Amedco do not imply either real or implied endorsement of any product, service, or company referred to in this educational activity.

Faculty

Gary Small, MD
Chair of Psychiatry, Hackensack University Medical Center
Behavioral Health Physician-in-Chief
Hovnanian Family Foundation Chair
Hackensack Meridian Health
Professor and Academic Chair of Psychiatry & Behavioral Health
Hackensack Meridian School of Medicine
Hackensack, NJ

Dr. Small discloses the following:
Advisory board: AARP, Acadia, Allergan, Avanir, Biogen, Electro Cellular Health Solutions, LLC, Gerontological Society of America, Handok, Herbalife, Lundbeck, Lilly, McCormick Science Institute, Merry Life Biomedical, Otsuka, Reckitt Benckiser, Roche, Theravalues
Equity interest: Ceremark Pharma, LLC

Paul Schulz, MD
Rick McCord Professor in Neurology
Umphrey Family Professor of Neurodegenerative Disorders
Director, Memory Disorders and Dementia Clinic
Director, Neuropsychiatry and Behavioral Neurology Fellowship
The McGovern Medical School of UTHealth Houston
Houston, TX

Dr. Schulz discloses the following:
Consultant: Eisai, Lilly, Acadia

Instructions

In order to receive CME/CE credits, participants must complete the pre-assessment questions, post-assessment, and program evaluation. Participants must also score at least 75% on the post-assessment. Certificates will be distributed online at the conclusion of the activity. Your online certificate will be saved on myCME within your Dashboard or Transcript, which you can access at any time.

For information about the accreditation of this program, please contact Sheryl@AmedcoEmail.com or 651-789-3730.

Privacy Policy

Amedco observes privacy and confidentiality of CME/CE information and personal information of CME/CE participants. Third parties receive only aggregated data about CME/CE activities relevant to their interests and/or the activities they support.

myCME privacy policy